Wellness & IV
EBOO Therapy: what it is, what to expect and where to find it
What is EBOO Therapy?
EBOO, short for extracorporeal blood oxygenation and ozonation, is a procedure offered by some wellness clinics in which blood is drawn, treated with ozone and oxygen outside the body, and returned. Clinics describe it as a form of ozone therapy; medical evidence for its benefits is limited, and it is usually self-pay.
How EBOO Therapy works
In a typical session a clinician places a line in a vein, and blood circulates through a sterile single-use set that exposes it to an ozone and oxygen mixture before returning it to the body. Clinics describe different session lengths and protocols. Because it involves the bloodstream, sterile technique, trained staff, appropriate equipment and an emergency plan are central questions.
What to expect at the appointment
- A medical screening covering your history, medicines and any conditions affecting the heart, blood or kidneys.
- Placement of a line in a vein by a trained clinician, with monitoring during the session.
- A session of a duration the clinic sets, during which your blood circulates through the treatment set.
- Aftercare instructions and a plan for follow-up sessions if the clinic recommends them.
Recovery and downtime
Clinics describe some people feeling tired or light-headed afterwards, with bruising or tenderness where the line was placed. Staff should advise on rest, fluids and activity. Contact the clinic or a doctor if you feel unwell.
Safety and suitability
- Ozone is regulated as a medical treatment in the United States, and published evidence for benefit is limited, so ask what the clinic claims and what it bases that on.
- Anyone with heart, blood, clotting or certain enzyme conditions, or who is pregnant, should speak to their own doctor before considering it.
- Risks include infection, vein irritation and reactions to the procedure, which the clinic should explain in writing.
- It is usually self-pay and sold as a course, so ask for the total cost before you commit.
Questions to ask before you book
- Who performs the procedure, and what are their licence and training?
- What equipment and single-use sets do you use, and how are they sterilised or disposed of?
- What medical screening do you do, and who should not have it?
- What do you tell patients about the evidence, and what happens if there is an emergency?
EBOO Therapy FAQ
What does EBOO stand for?
EBOO stands for extracorporeal blood oxygenation and ozonation. It describes a procedure in which blood is treated with ozone and oxygen outside the body before being returned.
Is EBOO an established medical treatment?
Published evidence for health benefits is limited, and claims made by clinics should be weighed against that. Ask any provider what they base their claims on, and speak to your own doctor.
Does insurance cover EBOO?
It is usually self-pay. Some people use payment plans or other financing, and whether pre-tax health account money applies depends on your plan and the reason for care, so ask the administrator first.
How is EBOO different from ozone therapy given another way?
Ozone therapy has several forms, including treating blood outside the body, injections and rectal or topical use. EBOO is the form that circulates blood through a treatment set, so equipment and sterility are especially important.
This is general information, not medical advice, and results differ from person to person. This treatment should be prescribed or performed by, or under the supervision of, a licensed medical provider. Talk to a licensed provider about your health history before booking.
Written and fact-checked against our editorial rules (no prices, statistics or promised results) by the MedSpa Listings editorial team. Last reviewed 2026-11-10.
Where to find EBOO Therapy
City pages for EBOO Therapy appear once at least three listed clinics in a city name it on their own website. Browse med spas by state.
Planning the cost? See how to pay for EBOO Therapy, including payment plans and HSA or FSA rules.